Pfizer’s COVID Vaccine may be less effective in obese people according to a new Italian study.
Severely overweight people are already considered to be more at risk of becoming critically ill or dying if they’re infected with the Coronavirus.
According to Italian researchers, obese people may need a 3rd shot, or two bigger doses, to protect themselves against the virus.
As the study showed severely overweight people only generated half the antibodies to fend off Covid after receiving two doses of the jab, compared to healthy people.
Scientists say this may be because they are more likely to have other conditions —such as diabetes and high blood pressure — that make them more vulnerable.
The Italian study, which has yet to be peered reviewed, is believed to be the first time the same link has been found for Covid.
Carrying added weight can lead to the immune system is constantly inflamed, impairing its function, according to experts.
For comparison, in healthy people, it only triggers inflammation when it is fighting an infection.
COVID Vaccine Study
The study followed 248 patients who received two doses of the Pfizer COVID-19 vaccine at the Rome-based Istituti Fisioterapici Ospitalieri.
Scientists analyzed their blood for levels of antibodies seven days after the second dose was administered.
Results showed that while those who were a normal weight had a high concentration (325.8), those who were obese had half this level (167.1), on average.
But the study only included 26 obese people, which is considered to be too small to draw concrete conclusions.
The study was only published as a pre-print on medRxiv, and its methodology and findings have yet to be peer-reviewed.
It also considered vaccine responses by age — but found no significant difference between the different groups.
Fat People COVID Vaccine Pool Wasn’t Big Enough
Professor Ian Jones, a virologist at the University of Reading stated that he thought the figures looked ‘suspiciously high’.
“It’s probably the small numbers (of participants). But that an effect is seen is not surprising.
It would be nothing to do with the vaccine, all would be similar. It is the individual’s response that is compromised.”
He added it was a ‘general finding’ that jabs are less effective in obese people.
‘It’s not entirely clear why but it may be related to metabolic syndrome which in turn has a knock-on effect to many cell functions, including immunity,’ he said.
Metabolic syndrome is the medical term for a cluster of conditions, including high blood pressure, heart disease, and type 2 diabetes.
But a separate study of obese Brazilian healthcare workers showed that reinfection with the coronavirus was also more common among fatties, since they tended to have lower antibody responses to the original infection.
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